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A dynamic team of faculty at the University of Utah is exploring the cellular processes behind psychostimulants like methamphetamine, amphetamine, and cocaine, along with the behavior of brain neurotransmitter and neuropeptide systems. Their research delves into the mechanisms of tolerance, dependence, addiction, and neurotoxicity linked to these substances, employing advanced in vitro and in vivo techniques. These methods span from analyzing gene expression in single neurons to tracking protein movement at a subcellular scale and observing whole-animal behavior. Additionally, their studies aim to uncover how neurotransmitters and neuropeptides interact, offering fresh perspectives on basal ganglia-related conditions such as Parkinson's Disease, addiction, Tourette syndrome, and obsessive-compulsive disorder.