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The Department of Molecular Genetics operates from the Medical Sciences Building, with close to 100 faculty members conducting research across multiple facilities including the Best Institute, Donnelly Centre for Cellular and Biomolecular Research, FitzGerald Building, Hospital for Sick Children, Mount Sinai Hospital, Ontario Institute for Cancer Research, and Princess Margaret Hospital.
Our Master of Science and PhD programs in Molecular Genetics provide research opportunities across diverse genetic systems, spanning from microorganisms to human subjects. Investigative areas encompass DNA repair mechanisms, gene expression control, cellular signaling pathways, host-pathogen interactions, developmental genetics in model organisms (including nematodes, fruit flies, and mice), neurobiology, immunology, cancer biology, structural biology, and human genetic therapies.
We stand at the brink of transformative medical breakthroughs driven by genetic and genomic innovations. The completion of the Human Genome Project has fundamentally reshaped biological and medical research. With the growing understanding of genomic sequences, technological advancements now enable rapid, cost-effective individual genome sequencing. Next-generation sequencing technologies have launched the age of precision genomic medicine, allowing researchers to detect genetic disorders, assess disease susceptibility, pinpoint modifying factors, and forecast medication responses based on personal genome data.