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The Department of Medical Biophysics is a multidisciplinary unit renowned for its pioneering work in cancer studies and broader biomedical fields. Based mainly at the Princess Margaret Cancer Centre, Sunnybrook Research Institute, and SickKids Research Institute, it provides graduate programs culminating in MSc and PhD degrees. This innovative program bridges biology, physics, clinical medicine, and engineering, offering cutting-edge education and top-tier research opportunities.
For over five decades, the department's graduate training initiative has been central to its mission, tracing its roots to cancer investigations at the Ontario Cancer Institute. It delivers research-intensive graduate programs at both MSc and PhD levels, with the doctoral program being the primary focus. Designed to complement students' undergraduate backgrounds in life or physical sciences, the curriculum typically takes 2.5 years for MSc candidates and 5-6 years for PhD students to complete.
Several faculty members specialize in examining protein structures and their molecular interactions to decipher biological mechanisms. This structural biology research employs techniques from molecular biology, biochemistry, and biophysics to determine 3D configurations of macromolecules, revealing their functional significance. Investigators utilize methods like X-ray crystallography, NMR spectroscopy, and cryo-EM to uncover molecular architectures and derive new biological understanding.