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The Department of Molecular Genetics operates from the Medical Sciences Building, with close to 100 faculty members conducting research across multiple facilities including the Best Institute, Donnelly Centre for Cellular and Biomolecular Research, FitzGerald Building, Hospital for Sick Children, Mount Sinai Hospital, Ontario Institute for Cancer Research, and Princess Margaret Hospital.
Our Master of Science and Doctor of Philosophy programs in Molecular Genetics provide research opportunities across diverse genetic systems, from microorganisms to human subjects. Investigative areas encompass DNA processes, gene regulation, cellular communication, host-pathogen interactions, developmental biology in various organisms, neurobiology, immunology, cancer research, structural biology, and human genetic therapies.
Researchers in our Genetic Models of Development and Disease division explore how genomic instructions guide multicellular organism formation, how these processes go awry in diseases like cancer, and how fundamental developmental pathways operate across species. The remarkable conservation of key regulatory mechanisms allows insights from simpler organisms to illuminate human development and genetic disorders, demonstrating how basic research can translate to medical applications.