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The biomedical informatics and computational biology (BICB) graduate program provides instruction across five foundational disciplines: 1) biochemistry, molecular and cellular biology, 2) database systems, data mining, and computing, 3) informatics, analytics, and machine learning, 4) mathematics, biostatistics, and statistical methods, and 5) computational and systems biology. Students can also choose electives from various domains such as chemistry, chemical engineering, physics, biophysics, structural biology, medical imaging, signal analysis, and clinical/translational sciences. Each student's curriculum is tailored to align with their academic interests and research focus, with potential credit given for relevant prior coursework. Participants may opt for a minor in another discipline. The program includes mandatory training in ethics, leadership, and management, covering legal matters, intellectual property, and business principles. Aspiring academics can engage in specialized teaching development programs. The M.S. degree offers two tracks: Plan A (thesis-based) and Plan B (project-based). Plan A is ideal for students aiming for research-oriented careers or future Ph.D. studies, as well as working professionals whose thesis can connect to their job responsibilities. Plan B better serves those seeking technical expertise over research experience in their professional settings.