PhD in Biomedical Sciences - Molecular Basis of Disease in Columbus United States | Ohio State University

Now that scientists have mapped the entire human genome, pinpointing genes associated with specific diseases has become significantly simpler compared to past decades. However, discovering a disease-causing gene doesn't automatically result in effective treatments. Creating therapies requires deep knowledge of when and where these genes are active, particularly how they operate in both healthy and diseased cells. The molecular basis of disease research focus aims to educate students in deciphering the molecular processes of disease-related genes across all illness types. Our methodology is fundamentally mechanistic, utilizing diverse techniques ranging from essential molecular, biochemical, and cellular biology methods to advanced live imaging, proteomics, and structural examination. We work with various experimental models, including cell cultures, yeast organisms, mice, and human tissue samples.