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Microbial pathogens encompass bacteria, viruses, fungi, and parasites, collectively responsible for a substantial portion of both acute and chronic illnesses in humans. Beyond investigating how these pathogens trigger diseases, microbial pathogenesis research also explores antibiotic resistance mechanisms and the creation of novel treatments and vaccines. Tackling essential questions about host-microbe relationships demands a multidisciplinary strategy, incorporating fields like microbiology, genomics, data science, molecular biology, biochemistry, immunology, and epidemiology. The foundational curriculum equips graduate students in microbial pathogenesis with core knowledge, while advanced courses, seminars, and journal clubs enable deeper exploration of microorganisms and the immune defenses vital to comprehending host-pathogen dynamics. The Center for Microbial Interface Biology further enriches graduate training opportunities in this field.