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Computational approaches and data analysis techniques are now indispensable in biological studies. Advanced technologies for gathering high-volume data, including genomic sequencing, mass spectrometry, and MRI imaging, along with the creation of extensive biological databases covering genomes, epidemiological records, and diverse biological datasets, have provided researchers with vast quantities of detailed information. This wealth of data demands sophisticated computational techniques for processing and interpretation. These analytical tools and datasets are revolutionizing nearly every aspect of biological science. Computational biologists tackle challenges ranging from studying disease genetics and comparing whole genomes to understand evolution, to predicting protein structures and interactions, developing new medications, simulating cellular signaling pathways, forecasting ecological responses to climate shifts, and creating conservation strategies for threatened species. Successful computational biologists need expertise in mathematics, statistics, machine learning, physical sciences, and biology. A crucial aspect of education in this field involves learning to connect biological phenomena with computational frameworks. At Cornell, researchers focus on six key computational biology specialties: 1. computational and statistical genomics, 2. population, comparative, and functional genomics, 3. bioinformatics, 4. proteomics, 5. ecology and evolutionary biology, and 6. statistical and computational modeling of biological systems.