PhD in Chemistry - Biological Inorganic Chemistry in York United Kingdom | University of York

Our studies center on the roles and uses of metal ions within living organisms.

Key research topics encompass:

The architecture, operations, and mechanisms of metalloproteins, particularly those involved in breaking down biomass, including lytic polysaccharide monooxygenases and hydrogenases
Proteins that bind siderophores
Engineered metalloenzymes

Investigations into siderophore-based compounds, carbon monoxide-releasing molecules, and redox-active bacterial enzymes aim to develop novel antimicrobial agents.

We employ diverse analytical approaches to examine proteins, with emphasis on structural analysis through magnetic spectroscopy, electrochemistry, and small molecule modeling. For organism-level studies, we utilize diagnostically-enhanced magnetic resonance imaging to track drug metabolism in real time via hyperpolarization techniques powered by molecular catalysts. These methods are complemented by density functional theory computations, genomic exploration, and chemical/molecular biology approaches.