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The Department of Molecular Genetics operates from the Medical Sciences Building, with close to 100 faculty members conducting research across multiple facilities including the Best Institute, Donnelly Centre for Cellular and Biomolecular Research, FitzGerald Building, Hospital for Sick Children, Mount Sinai Hospital, Ontario Institute for Cancer Research, and Princess Margaret Hospital.
The Molecular Genetics graduate programs (MSc and PhD) provide research opportunities across diverse genetic models, from microorganisms to humans. Investigative areas encompass DNA processes, gene regulation, cellular communication, host-pathogen interactions, developmental genetics in model organisms, neurobiology, immunology, cancer research, structural biology, and human genetics with therapeutic applications.
Computational biology utilizes data analysis techniques to decipher complex biological systems through genomic data interpretation. Systems biology examines biological networks holistically, requiring both experimental and computational approaches to uncover emergent properties. These complementary disciplines work together to elucidate cellular mechanisms, identify disease pathways, and develop targeted treatments.