PhD in Molecular Genetics - Functional Genomics and Proteomics in Toronto Canada | University of Toronto

The Department of Molecular Genetics operates from the Medical Sciences Building, with close to 100 faculty members conducting research across multiple facilities including the Best Institute, Donnelly Centre for Cellular and Biomolecular Research, FitzGerald Building, Hospital for Sick Children, Mount Sinai Hospital, Ontario Institute for Cancer Research, and Princess Margaret Hospital.
Our Master of Science and PhD programs in Molecular Genetics provide research opportunities across diverse genetic systems, from microorganisms to human subjects. Investigative work spans DNA repair mechanisms, gene regulation, developmental genetics in model organisms, molecular immunology, cancer biology, structural biology, and therapeutic gene applications.
Functional Genomics and Proteomics research at MoGen employs cutting-edge techniques to decode how genetic and protein information operates within living systems. This work systematically examines fundamental cellular mechanisms governing growth and development while identifying disease-related alterations. These emerging biological fields leverage technological innovations, particularly in DNA sequencing (pioneered during the Human Genome Project) and mass spectrometry (for molecular identification and quantification). Modern sequencing capabilities now enable complete individual genome mapping and comprehensive RNA profiling, while mass spectrometry provides crucial protein expression data that complements nucleic acid sequencing information. These high-throughput, frequently automated methodologies generate complex datasets analyzed through advanced computational approaches.