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The Human and Translational Immunology (HTI) Program at Yale School of Medicine aims to swiftly translate cutting-edge immunology research into treatments for human diseases. Based administratively in the Department of Immunobiology with core labs located in the Amistad building and George Street Facility, HTI welcomes all Yale School of Medicine faculty engaged in human immunology research and its role in disease. HTI researchers explore immunological factors across a wide spectrum of conditions, including cancer therapies, organ and stem cell transplantation, autoimmune disorders (such as Type 1 diabetes, rheumatoid arthritis, and lupus), respiratory illnesses (like asthma and COPD), neurological conditions (including multiple sclerosis), and digestive disorders (such as Crohn's disease, celiac sprue, and ulcerative colitis). The program fosters collaboration between clinical and basic science researchers while providing essential resources for human disease treatment studies. A key HTI focus is supporting early-stage (Phase I/II) therapeutic development and facilitating applications to major research networks like the Immune Tolerance Network, FOCIS Centers of Excellence, and Trialnet.