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Neuroimaging and optogenetics serve as powerful research tools, with modern neuroimaging revolutionizing how we examine dynamic nervous system processes non-invasively, quickly, and in real time. The University of Minnesota boasts one of the globe's leading high and ultrahigh field functional magnetic resonance imaging (fMRI) facilities at its Center for Magnetic Resonance Research. Initially supported by the National Center for Research Resources and currently funded by the National Institute of Biomedical Imaging and Bioengineering, this Center specializes not just in fundamental brain research but also in pioneering novel techniques and equipment for gathering structural, functional, and biochemical data non-invasively from both animal models and humans. Equipped with ultrahigh field magnets (7 tesla and higher), the Center features some of the most sophisticated MR technology worldwide. Furthermore, the Veterans Administration Medical Center operates a magnetoencephalography (MEG) system employing over 200 axial gradiometers to detect minute magnetic fields generated by neural activity. These cutting-edge neuroimaging resources provide Neuroscience Graduate Program faculty and students with significant technological benefits. Optogenetics, another breakthrough method, enables light-based control of genetically altered nervous system cells containing light-sensitive ion channels. This innovation dramatically enhanced our capacity to manipulate and observe individual neurons in living tissue while assessing these interventions in real time.