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The University of Michigan's computer networks research adopts a comprehensive, system-wide approach, spanning from mobile computing and wireless technologies to datacenter architectures and global Internet systems. On the front-end, our efforts focus on optimizing web interfaces and mobile applications to enhance speed and usability, while strengthening the dependability of service infrastructures for end-user delivery. Our wireless and mobile investigations explore hardware-software integration, specializing in adaptive network systems, cognitive radio technology, spectrum analysis, MAC/network protocols, and mobile platform development. For data center environments, we prioritize network-application synergy, developing coflow-based networking solutions and infrastructure-conscious application designs. Our operating systems and distributed systems research addresses emerging challenges across embedded devices, sensor arrays, cloud platforms, and global web services. Modern operating systems now permeate everyday technology, governing not only conventional computers and cloud networks but also smart devices and critical infrastructure like vehicles and energy systems. Michigan's research initiatives employ innovative methods—including deterministic replay, redundant processing, erasure coding, and system-application co-design—to improve the security, efficiency, scalability, and manageability of individual devices, data centers, and worldwide web services.