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Genome sequencing offers an impartial, comprehensive perspective on biological systems by mapping entire gene collections. Research initiatives at Berkeley span from genome sequencing, classification, and examination of both novel and model organisms at Lawrence Berkeley National Laboratory and the Joint Genomics Institute, to theoretical and experimental studies on genetic circuitry. Computational techniques help uncover hidden molecular and cellular processes, create digital searches for genetic regulators, and conduct in-depth analyses of biochemical and genetic networks that control cellular growth—ultimately aiming to engineer cellular and tissue systems.
At Berkeley, computational methods also contribute to deciphering protein folding principles, designing proteins (particularly enzymes), analyzing signaling networks that regulate cell specialization and movement, simulating energy dynamics in motor proteins, ion channels, and pumps, modeling population and disease patterns, understanding neural network information processing in vision, hearing, and learning, and developing computer vision systems.