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The Department of Physiology and Biophysics provides a doctoral program culminating in a Ph.D. degree. Faculty members' wide-ranging expertise enables research opportunities spanning systems physiology, cancer translation studies, and single-molecule biophysical investigations. We aim to train students in applying quantitative approaches to examine intricate physiological challenges related to human health and disorders. Key research focuses include: 1) Biophysical studies of ion channels and gap junctions, particularly in cardiac and visual systems, 2) Cellular communication pathways in oncology and neuroscience, 3) Physiological investigations across cellular, organ, and whole-animal levels using transgenic disease models, and 4) Advanced fluorescence microscopy, featuring Stony Brook University's most extensive microscopy facilities. The program builds upon core Human Physiology instruction, supplemented by specialized courses in Statistical Methods, Biochemistry, and Biomembrane physical chemistry. Students can customize their education through electives in Applied Mathematics, Genetics, Neurobiology, or Journalism to align with professional aspirations. Graduates pursue diverse careers in academic research, pharmaceutical development, public policy, and legal fields.