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Biostatistics tackles statistical challenges in biological, medical, and public health research. This field encompasses areas like epidemiology, clinical studies, longevity research, and medical imaging techniques. When examining extensive genetic data or investigating intricate gene interactions and environmental influences, these studies fall under bioinformatics, genetic statistics, or systems biology. Faculty members from our department and collaborating researchers at M.D. Anderson Cancer Center pioneer innovative approaches in biostatistical and genomic analysis, often focusing on contemporary issues related to massive datasets, high-dimensional analysis, and complex biological systems. Solutions for these challenges may involve techniques such as data synthesis, forecasting, statistical artificial intelligence, Bayesian frameworks, causal analysis, and network modeling.