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Biomaterials science explores the interaction between natural/synthetic materials and living systems. These include everything from inert joint replacements to bioinspired scaffolds that encourage tissue regeneration by stimulating the body's natural healing processes. The Weldon School of Biomedical Engineering conducts comprehensive research across this dynamic field. Investigations range from analyzing how extracellular matrix components guide cellular behavior to creating innovative polymer-based biomaterials, with faculty and students pioneering methods to replace, restore, or regrow tissues affected by injury or illness.
Key factors driving biomaterial and implant development include the mechanical conditions of the target area and cellular responses to physical forces, a field called mechanobiology. By examining the structural properties of different tissue elements, scientists are enhancing both our knowledge of human physiology and the medical devices used for bodily repair. The Weldon School's biomechanics research employs both experimental and computational approaches across various scales - from analyzing whole-body responses to external forces to measuring how microscopic cellular deformations affect genetic activity.
The multidisciplinary researchers at the Weldon School of Biomedical Engineering are expanding upon a strong legacy of innovation. Their work encompasses early detection techniques for microscopic bone fractures and smart implants capable of self-monitoring and environmental sensing, all contributing to groundbreaking medical knowledge and therapies that will transform how we understand and heal the human body.