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Plant genetic blueprints contain solutions to pressing worldwide challenges, including ensuring future food supplies and addressing climate change. The Plant Genomics Research initiative at NYU Biology utilizes and pioneers advanced techniques in Genomics, Bioinformatics & Systems Biology to reveal how plants develop, thrive, adjust, and evolve within their ecosystems. This program focuses on four interrelated research domains: Genetic and Genomic Studies of Plant Development, Systems Biology and Gene Regulation in Plants, Evolutionary Genomics and Agricultural Domestication, and Plant Adaptation to Environmental Stress. Our genomic investigations cover diverse species, from Arabidopsis models and their natural variants to cultivated crops and representatives across major plant lineages. We examine plant life at every scale, from individual cells to complete organisms, employing integrated genomic, computational, evolutionary, and systems biology methodologies.