PhD in Cardiovascular - Exercise and The Failing Heart in Leeds United Kingdom | University of Leeds

Pursuing a research degree in the Faculty of Biological Sciences allows you to cultivate expertise as an autonomous investigator in your selected discipline. Guided by your principal supervisor and additional co-supervisors, you'll conduct pioneering investigations into specific biological challenges while joining an extensive research network employing interdisciplinary methods to address contemporary scientific inquiries. During your doctoral studies, you'll not only enhance your specialized research capabilities but also acquire valuable skills through structured training initiatives, seminar participation, and conference engagements.

Heart failure represents a multifaceted condition involving compromised cardiac, pulmonary, musculoskeletal, and vascular performance, collectively diminishing life quality and increasing mortality risk. While exercise demonstrates proven advantages for heart failure patients, discussions persist regarding optimal exercise protocols. Our studies examine how the multi-system dysfunctions typical of heart failure collectively contribute to fatigue, exercise limitations, reduced life quality, and ultimately survival rates. We investigate the physiological mechanisms underlying exercise's therapeutic effects and identify the most effective training approaches to maximize benefits. Our methodologies span from genetic expression analysis to in vivo organ assessment, supplemented by computational modeling techniques.